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Department of Bioorganic Chemistry

Mussa Khamis

Born: January 25, 1993, at Zanzibar, Tanzania.khamis2.jpg

Room: 107, building A2

Phone: +48 512 739 119

e-mail: mussa-yussuf.khamis@pwr.edu.pl

ORCID: 0000-0002-1197-3989

Hobby: Sporting (running and badminton), Content creator, Story-telling writer,  Drawing, Cooking, Travelling, Speaking multiple languages (French, English, Swahili and Chinese

 

Research

Design and synthesis of peptidomimetics containing triazole rings as potential inhibitors of tyrosinase.

Keywords     

Peptides, small molecules, peptidomimetics, structure-activity relationship (SAR), NMR spectroscopy, molecular modelling, Synthesis, Cancer treatment

Education

2025 - PhD studies in Chemical Sciences; Department of Bioorganic Chemistry, Wroclaw University of Science and Technology, Poland.

2021 - MSc in Medicinal Chemistry, School of Pharmaceutical Sciences, Zhengzhou University, China

2018 - Bachelor of Process Engineering, Faculty of Material Sciences, University of Science and Technology of Oran, Algeria.

Experience

  • Industrial training to work on operating and analysing the dairy products at AZAM Diary Product Limited. In Zanzibar, Tanzania.
  • Laboratory training to analyse water samples from Oran city in Algeria.

Publications

  1. Gramine-based structure optimization to enhance anti-gastric cancer activity. Xin-Hui Zhang, Qian Guo, Heng-Ying Wang, Yi-Han Li, Mussa Yussuf Khamis, Li-Ying Ma, Bo Wang, and Hong-Min Liu. Journal of Bioorganic Chemistry https://doi.org/10.1016/j.bioorg.2020.104549.
  2. Overcome the tumour immunotherapy resistance by combination of the HDAC6 inhibitors with antitumor immunomodulatory agents. Mussa Yussuf Khamis, Hui-Pan Wu, Qin Ma, Yi-Han Li, Li-Ying Ma, Xin-Hui Zhang, and Hong-Min Liu. [J] Bioorganic Chemistry. https://doi.org/10.1016/j.bioorg.2021.104754.
  3. A Review of Progress in Histone Deacetylase 6 Inhibitors Research: Structural Specificity and Functional Diversity. Xin-Hui Zhang, Qin-Ma, Hui-Pan Wu, Mussa Yussuf Khamis, Yi-Han Li, Li-Ying Ma, Hong-Min Liu. Journal of Medicinal Chemistry. PMID: 33523672. DOI: 10.1021/acs.jmedchem.0c01782.
  4. Arsene T K, Kilembe J T, Matondo A, Yussuf K M, Nininahazwe L, Nkatu F K, Tshingamb M N, Vangu E K, Kindala J T, Mihigo S O, Kayembe S J, Kafuti Y S, Clement A, Taba K M. Computational analysis by molecular docking of thirty alkaloid compounds from medicinal plants as potent inhibitors of SARS-CoV-2 main protease. Journal of Comput Chem Mol Model.2020; 4(4):487-503. doi:10.25177/JCCMM.4.4.RA.10699

 

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