Born: May 10^th, 1991 in Świdnica, Poland

Room: 302 (or 324), building A-2

Phone: +48 71 320 37 04

e-mail: pawel.nocen@pwr.edu.pl, nocen91@gmail.com

Hobby: football (actively as a player and passively as a spectator), foreign languages, cross-country skiing.

ORCID: 0000-0003-4743-8352

Google Scholar: jkeyIBgAAAAJ

Web of Science ID: HKM-8389-2023

Research:

synthesis of miniproteins displaying inhibitory activity towards protein-protein interactions, physicochemical analysis of the synthesized products; designing of peptides and miniproteins for medicinal chemistry purposes

Education:

2020 – now - Doctoral School, Department of Bioorganic Chemistry, Faculty of Chemistry, Wroclaw University of Science and Technology

2017 – 2019 - Doctoral Studies [not finished], Laboratory of Medical Biology, Faculty of Biotechnology, University of Wroclaw

2015 – 2017 - Doctoral Studies, Cytobiochemistry Department, Faculty of Biotechnology, University of Wroclaw

2014 – 2015 - Master Studies in Medicinal Chemistry, Wroclaw University of Science and Technology

2010 – 2014 - Bachelor Studies in Biotechnology, Wroclaw University of Science and Technology

2008 – 2010 - Jan Kasprowicz Secondary School No. 1 in Świdnica, profile Biology and Chemistry

Prizes

“Poster Presentation Award for outstanding scientific research and excellent poster presentation” – during 26^th Polish Peptide Symposium (Stare Jabłonki, Poland, 3^rd-7^th June 2023)

Posters

Main authorship

1. “Comparative study of miniproteins derived from two different scaffolds – investigation of inhibitory activity against PD-1/PD-L1 interaction” – 26^th Polish Peptide Symposium (Stare Jabłonki, Poland, 3^rd-7^th June 2023)
2. “Validation of the choice of a miniprotein scaffold used for the obtainment of inhibitors targeted towards PD-1 protein” - ChemBiotIC 2023, Chemistry & Biotechnology International Conference (Wrocław, Poland, 22^nd-23^rd June 2023)
3. “Synthesis and inhibitory activity of PD-1-targeted peptides derived from sequences of MvaT and ENH miniproteins” – 64^th Congress of Polish Chemical Society (Lublin, Poland, 18^th-22^nd September 2022)
4. „Novel PD-1-targeted inhbitors of PD-1/PD-L1 interaction designed basing on the MvaT miniprotein structure” – EFMC International Symposium on Medicinal Chemistry (online event, 29^th August - 2^nd  September 2021)
5. „An approach to design and synthesize miniproteins binding to PD-1 receptor” - ChemBiotIC, Chemistry & Biotechnology International Conference (Wrocław, Poland, 24^th-25^th June 2021)

Co-authorship

1. 1. „Porphyromonas gingivalis HmuY and Tannerella forsythia Tfo - two homologous proteins with different heme-binding properties” - 43^rd FEBS Congress (Prague, Czech Republic, 7^th-12^th July 2018)
2. „Prevotella intermedia produces two homologous proteins to Porphyromonas gingivalis HmuY with different heme-binding properties” - 43^rd FEBS Congress (Prague, Czech Republic, 7^th-12^th July 2018)
3. „Human α1,4-galactosyltransferase (Gb3/CD77 synthase): how one amino acid residue may drive promiscuity of a glycosyltransferase” – 23^rd International Symposium on Glycoconjugates „GLYCO 23” (Split, Croatia, 15^th-20^th September 2015)
4. „Revisiting the mystery of P1PK (formerly P) blood group system: recombinant human Pk synthase (alpha-1,4-galactosyltransferase) synthesizes both Pk and P1 antigens” - Gordon Research Conference (Glycobiology): Glycans as Mediators of Interactions Between Molecules, Cells and Organisms (Lucca, Italy, 1^st-6^th March 2015)
5. „Human Gb3/CD77 synthase (α1,4-galactosyltransferase): the first known enzyme that changes acceptor specificity as a result of a point mutation, resulting in synthesis of NOR blood group antigen” - presented at the 9^th International Symposium on Glycosyltransferases (Porto, Portugal, 18^th-21^st June 2014)